The Van Doorslaer lab at the University of Arizona

Publications involving our group at the University of Arizona

  1. Fish Polyomaviruses belong to two distinct evolutionary lineagesVan Doorslaer K, Kraberger S, Austin C, Farkas K, Bergeman M, Paunil E, Davison W, Varsani A. J Gen Virol. 2018 Accepted for Publication
  2. Diverse papillomaviruses identified in Weddell seals. Smeele ZE, Burns JM, Van Doorslaer K, Fontenele RS, Waits K, Stainton D, Shero MR, Beltran RS, Kirkham AL, Berngartt R, Kraberger S, Varsani A.J Gen Virol. 2018 Feb 22. doi: 10.1099/jgv.0.001028. Pubmed
  3. Roles of APOBEC3A and APOBEC3B in Human Papillomavirus Infection and Disease Progression. Warren CJ, Westrich JA, Van Doorslaer K, Pyeon D.Viruses. 2017 Aug 21;9(8). pii: E233. doi: 10.3390/v9080233. Pubmed
  4. Persistence of an Oncogenic Papillomavirus Genome Requires cis Elements from the Viral Transcriptional Enhancer.Van Doorslaer K, Chen D, Chapman S, Khan J, McBride AA. Mbio. 2017 Nov 21;8(6). pii: e01758-17. doi: 10.1128/mBio.01758-17. Pubmed
  5. Unique genome organization of non-mammalian papillomaviruses provides insights into the evolution of viral early proteins. Van Doorslaer K, Ruoppolo V, Schmidt A, Lescroƫl A, Jongsomjit D, Elrod M, Kraberger S, Stainton D, Dugger KM, Ballard G, Ainley DG, Varsani A. Virus Evol. 2017 Oct 6;3(2):vex027. doi: 10.1093/ve/vex027. eCollection 2017 Jul. Pubmed
  6. The Papillomavirus Episteme: a major update to the papillomavirus sequence database. Van Doorslaer K, Li Z, Xirasagar S, Maes P, Kaminsky D, Liou D, Sun Q, Kaur R, Huyen Y, McBride AA. Nucleic Acids Res. 2017 Jan 4;45(D1):D499-D506. doi: 10.1093/nar/gkw879. Epub 2016 Oct 5. Pubmed
  7. Novel recombinant papillomavirus genomes expressing selectable genes. Van Doorslaer K, Porter S, McKinney C, Stepp WH, McBride AA. Sci Rep. 2016 Nov 28;6:37782. doi: 10.1038/srep37782. Pubmed
  8. Detection and genotyping of Alpha Human Papillomaviruses from archival formalin fixed tissue samples. Van Doorslaer K, Chen Z, and McBride AA. Curr Protoc Microbiol. 2016 Nov 18;43:14B.9.1-14B.9.20. doi: 10.1002/cpmc.16. Pubmed
  9. The Papillomavirus Episteme: a major update to the papillomavirus sequence database. Van Doorslaer K, Li Z, Xirasagar S, Maes P, Kaminsky D, Liou D, Sun Q, Kaur R, Huyen Y, McBride AA. Nucleic Acids Res. 2017 Jan; doi: 10.1093/nar/gkw879. Epub 2016 Oct 5. Pubmed
  10. Molecular archeological evidence in support of the repeated loss of a papillomavirus gene. Van Doorslaer K and McBride AA. Sci Rep. 2016 Sep 8;6:33028. doi: 10.1038/srep33028. Pubmed
  11. The Ancient Evolutionary History of Polyomaviruses. Buck CB, Van Doorslaer K, Peretti A, An P, Katz J, Pipas J, McBride AA, Camus A, McDermott A, Dill J, Delwart E, Ng TFN, Farkas K, Austin C, Kraberger S, Davison W, Pastrana D and Varsani A. PLoS Pathog. 2016 Apr 19;12(4):e1005574. doi: 10.1371/journal.ppat.1005574. eCollection 2016 Apr. Pubmed
  12. Papillomavirus Evolution Driven by the Host Restriction Factor APOBEC3 and DNA Methylation. Van Doorslaer K, Warren CJ, Pandey A, Espinosa JM, Dohun P. Virus Evol 2015 1 (1): vev015 DOI: Pubmed
  13. UbSRD: The Ubiquitin Structural Relational Database. Harrison JS, Jacobs TM, Houlihan K, Van Doorslaer K and Kuhlman B. J Mol Biol. 2015 Sep 18. pii: S0022-2836(15)00522-7. doi: 10.1016/j.jmb.2015.09.011. Pubmed
  14. Degradation of human PDZ-proteins by human Alphapapillomaviruses represents an evolutionary adaptation to a novel cellular niche. Van Doorslaer K, DeSalle R, Einstein MH and Burk RD. PLoS Pathog. 2015 Jun 18;11(6):e1004980. doi: 10.1371/journal.ppat.1004980. eCollection 2015 Jun. Pubmed
  15. A Proteomic approach to discover and compare interacting partners of Papillomavirus E2 proteins from diverse phylogenetic groups. Jang MK, Anderson DE, Van Doorslaer K and McBride AA. Proteomics. 2015 Mar 11. doi: 10.1002/pmic.201400613. Pubmed
  16. Evolution of the Papillomaviridae. Van Doorslaer K. Virology. 2013 Oct;445(1-2):11-20. doi: 10.1016/j.virol.2013.05.012. Epub 2013 Jun 14. Pubmed
  17. Condylomatous genital lesions in cynomolgus macaques from Mauritius. Harari A, Wood CE, Van Doorslaer K, Chen Z, Domaingue MC, Elmore D, Koenig P, Wagner JD, Jennings RN and Burk RD. Toxicol Pathol. 2013 Aug;41(6):893-901. doi: 10.1177/0192623312467521. Epub 2012 Dec 21. Pubmed
  18. The Papillomavirus Episteme: a central resource for papillomavirus sequence data and analysis. Van Doorslaer K, Tan Q, Xirasagar S, Bandaru S, Gopalan V, Mohamoud Y, Huyen Y and McBride AA. Nucleic Acids Res. 2013 Jan;41(Database issue):D571-8. doi: 10.1093/nar/gks984. Epub 2012 Oct 23. Pubmed
  19. Association between hTERT activation by HPV E6 proteins and oncogenic risk. Van Doorslaer K and Burk RD. Virology. 2012 Nov 10;433(1):216-9. doi: 10.1016/j.virol.2012.08.006. Epub 2012 Aug 25. Pubmed
  20. Sequence imputation of HPV16 genomes for genetic association studies. Smith B, Chen Z, Reimers L, Van Doorslaer K, Schiffman M, Desalle R, Herrero R, Yu K, Wacholder S, Wang Tand Burk RD. PLoS One. 2011;6(6):e21375. doi: 10.1371/journal.pone.0021375. Epub 2011 Jun 23. Pubmed
  21. Novel betapapillomavirus associated with hand and foot papillomas in a cynomolgus macaque. Wood CE, Tannehill-Gregg SH, Chen Z, Van Doorslaer K, Nelson DR, Cline JM, Burk RD.Vet Pathol. 2011 May;48(3):731-6. doi: 10.1177/0300985810383875. Epub 2010 Oct 4. Pubmed
  22. Papillomaviruses: evolution, Linnaean taxonomy and current nomenclature. Van Doorslaer K, Bernard HU, Chen Z, de Villiers EM, zur Hausen H and Burk RD. Trends Microbiol. 2011 Feb;19(2):49-50; author reply 50-1. doi: 10.1016/j.tim.2010.11.004. Epub 2010 Dec 7. Pubmed
  23. Evolution of human papillomavirus carcinogenicity. Van Doorslaer K and Burk RD. Adv Virus Res. 2010;77:41-62. doi: 10.1016/B978-0-12-385034-8.00002-8. Review. Pubmed
  24. Degradation of p53 by human Alphapapillomavirus E6 proteins shows a stronger correlation with phylogeny than oncogenicity. Fu L, Van Doorslaer K, Chen Z, Ristriani T, Masson M, Travé G and Burk RD. PLoS One. 2010 Sep 17;5(9). doi:pii: e12816. 10.1371/journal.pone.0012816. Pubmed
  25. Overexpression of miR-21 promotes an in vitro metastatic phenotype by targeting the tumor suppressor RHOB. Connolly EC, Van Doorslaer K, Rogler LE and Rogler CE. Mol Cancer Res. 2010 May;8(5):691-700. doi: 10.1158/1541-7786.MCR-09-0465. Epub 2010 May 11. Pubmed
  26. Classification of papillomaviruses (PVs) based on 189 PV types and proposal of taxonomic amendments. Bernard HU, Burk RD, Chen Z, Van Doorslaer K, zur Hausen H and de Villiers EM. Virology. 2010 May 25;401(1):70-9. doi: 10.1016/j.virol.2010.02.002. Epub 2010 Mar 5. Pubmed
  27. Lack of heterogeneity of HPV16 E7 sequence compared with HPV31 and HPV73 may be related to its unique carcinogenic properties. Safaeian M, Van Doorslaer K, Schiffman M, Chen Z, Rodriguez AC, Herrero R, Hildesheim A and Burk RD. Arch Virol. 2010 Mar;155(3):367-70. doi: 10.1007/s00705-009-0579-2. Epub 2010 Jan 6. Pubmed
  28. Genomic diversity and interspecies host infection of alpha12 Macaca fascicularis papillomaviruses (MfPVs). Chen Z, Van Doorslaer K, DeSalle R, Wood CE, Kaplan JR, Wagner JD and Burk RD. Virology. 2009 Oct 25;393(2):304-10. doi: 10.1016/j.virol.2009.07.012. Epub 2009 Aug 28. Pubmed
  29. Human papillomaviruses: genetic basis of carcinogenicity. Burk RD, Chen Z and Van Doorslaer K. Public Health Genomics. 2009;12(5-6):281-90. doi: 10.1159/000214919. Epub 2009 Aug 11. Review. Pubmed
  30. Serological response to an HPV16 E7 based therapeutic vaccine in women with high-grade cervical dysplasia. Van Doorslaer K, Reimers LL, Studentsov YY, Einstein MH and Burk RD. Gynecol Oncol. 2010 Feb;116(2):208-12. doi: 10.1016/j.ygyno.2009.05.044. Epub 2009 Jun 24. Pubmed
  31. Identification of unusual E6 and E7 proteins within avian papillomaviruses: cellular localization, biophysical characterization, and phylogenetic analysis. Van Doorslaer K, Sidi AO, Zanier K, Rybin V, Deryckère F, Rector A, Burk RD, Lienau EK and Van Ranst M, Travé G. J Virol. 2009 Sep;83(17):8759-70. doi: 10.1128/JVI.01777-08. Epub 2009 Jun 24. Pubmed
  32. Macaca fascicularis papillomavirus type 1: a non-human primate betapapillomavirus causing rapidly progressive hand and foot papillomatosis. Joh J, Hopper K, Van Doorslaer K, Sundberg JP, Jenson AB and Ghim SJ. J Gen Virol. 2009 Apr;90(Pt 4):987-94. doi: 10.1099/vir.0.006544-0. Epub 2009 Mar 4. Pubmed
  33. A single amino acid substitution in a segment of the CA protein within Gag that has similarity to human immunodeficiency virus type 1 blocks infectivity of a human endogenous retrovirus K provirus in the human genome. Heslin DJ, Murcia P, Arnaud F, Van Doorslaer K, Palmarini M and Lenz J. J Virol. 2009 Jan;83(2):1105-14. doi: 10.1128/JVI.01439-08. Epub 2008 Nov 12. Pubmed
  34. Genomic characterization of two novel reptilian papillomaviruses, Chelonia mydas papillomavirus 1 and Caretta caretta papillomavirus 1. Herbst LH, Lenz J, Van Doorslaer K, Chen Z, Stacy BA, Wellehan JF Jr, Manire CA and Burk RD. Virology. 2009 Jan 5;383(1):131-5. doi: 10.1016/j.virol.2008.09.022. Epub 2008 Oct 29.Pubmed
  35. Genomic characterization of novel dolphin papillomaviruses provides indications for recombination within the Papillomaviridae. Rector A, Stevens H, Lacave G, Lemey P, Mostmans S, Salbany A, Vos M, Van Doorslaer K, Ghim SJ, Rehtanz M, Bossart GD, Jenson AB and Van Ranst M. Virology. 2008 Aug 15;378(1):151-61. doi: 10.1016/j.virol.2008.05.020. Epub 2008 Jun 24. Pubmed
  36. Ancient papillomavirus-host co-speciation in Felidae. Rector A, Lemey P, Tachezy R, Mostmans S, Ghim SJ, Van Doorslaer K, Roelke M, Bush M, Montali RJ, Joslin J, Burk RD, Jenson AB, Sundberg JP, Shapiro B and Van Ranst M. Genome Biol. 2007;8(4):R57. Pubmed
  37. Complete genomic characterization of a murine papillomavirus isolated from papillomatous lesions of a European harvest mouse (Micromys minutus). Van Doorslaer K, Rector A, Jenson AB, Sundberg JP, Van Ranst M and Ghim SJ. J Gen Virol. 2007 May;88(Pt 5):1484-8. Pubmed
  38. Genetic characterization of the first chiropteran papillomavirus, isolated from a basosquamous carcinoma in an Egyptian fruit bat: the Rousettus aegyptiacus papillomavirus type 1. Rector A, Mostmans S, Van Doorslaer K, McKnight CA, Maes RK, Wise AG, Kiupel M and Van Ranst M. Vet Microbiol. 2006 Oct 31;117(2-4):267-75. Epub 2006 Jul 18. Pubmed
  39. Genetic characterization of the Capra hircus papillomavirus: a novel close-to-root artiodactyl papillomavirus. Van Doorslaer K, Rector A, Vos P and Van Ranst M. Virus Res. 2006 Jun;118(1-2):164-9. Epub 2006 Jan 23. Pubmed
  40. Isolation and cloning of the raccoon (Procyon lotor) papillomavirus type 1 by using degenerate papillomavirus-specific primers. Rector A, Van Doorslaer K, Bertelsen M, Barker IK, Olberg RA, Lemey P, Sundberg JP and Van Ranst M. J Gen Virol. 2005 Jul;86(Pt 7):2029-33. Pubmed
  41. Isolation and cloning of a papillomavirus from a North American porcupine by using multiply primed rolling-circle amplification: the Erethizon dorsatum papillomavirus type 1. Rector A, Tachezy R, Van Doorslaer K, MacNamara T, Burk RD, Sundberg JP and Van Ranst M. Virology. 2005 Jan 20;331(2):449-56. Pubmed